MMDPDAMedical & Dental Professional Development Alliance
Evidence for clinical practice

Clinical Knowledge

Structured, referenced clinical resources for healthcare professionals, organised by specialty, profession and resource type, with transparent review and evidence metadata.

300 clinical resources
Clinical practice guide

Superior vena cava obstruction: oncological assessment and urgent management

An evidence-informed international clinical reference on superior vena cava obstruction, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Malignant spinal cord compression: emergency recognition and definitive treatment

An evidence-informed international clinical reference on malignant spinal cord compression, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Cancer-associated venous thromboembolism: anticoagulation and bleeding risk

An evidence-informed international clinical reference on cancer-associated venous thromboembolism, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Melanoma systemic therapy: immunotherapy, targeted therapy and toxicity

An evidence-informed international clinical reference on melanoma systemic therapy, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Head and neck squamous cell carcinoma: airway, staging and organ-preserving treatment

An evidence-informed international clinical reference on head and neck squamous cell carcinoma, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Cervical cancer: abnormal bleeding, staging and definitive treatment

An evidence-informed international clinical reference on cervical cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Endometrial cancer: postmenopausal bleeding, staging and adjuvant treatment

An evidence-informed international clinical reference on endometrial cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Ovarian cancer: adnexal mass assessment, cytoreduction and systemic therapy

An evidence-informed international clinical reference on ovarian cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Pancreatic cancer: diagnostic pathway, resectability and supportive care

An evidence-informed international clinical reference on pancreatic cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Colorectal cancer: diagnosis, staging and perioperative treatment

An evidence-informed international clinical reference on colorectal cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Small-cell lung cancer: staging, systemic therapy and thoracic treatment

An evidence-informed international clinical reference on small-cell lung cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Metastatic prostate cancer: androgen deprivation and treatment intensification

An evidence-informed international clinical reference on metastatic prostate cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Breast cancer: triple assessment, staging and multidisciplinary treatment

An evidence-informed international clinical reference on breast cancer, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

OncologyReviewed 2026-08-18
Clinical practice guide

Glucocorticoid-induced osteoporosis: fracture-risk assessment and prevention

An evidence-informed international clinical reference on glucocorticoid-induced osteoporosis, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

RheumatologyReviewed 2026-08-18
Clinical practice guide

Fibromyalgia: diagnosis, function and multimodal symptom management

An evidence-informed international clinical reference on fibromyalgia, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

RheumatologyReviewed 2026-08-18
Clinical practice guide

Antiphospholipid syndrome: thrombosis, pregnancy morbidity and anticoagulation

An evidence-informed international clinical reference on antiphospholipid syndrome, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

RheumatologyReviewed 2026-08-18