MMDPDAMedical & Dental Professional Development Alliance
Evidence for clinical practice

Clinical Knowledge

Structured, referenced clinical resources for healthcare professionals, organised by specialty, profession and resource type, with transparent review and evidence metadata.

600 clinical resources
Clinical practice guide

Wilson disease: diagnosis, copper assessment and long-term treatment

An evidence-informed international clinical reference on wilson disease, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Alcohol-associated hepatitis: severity, nutrition and treatment selection

An evidence-informed international clinical reference on alcohol-associated hepatitis, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Hepatorenal syndrome: diagnosis, albumin, vasoconstrictors and transplant assessment

An evidence-informed international clinical reference on hepatorenal syndrome, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Portal vein thrombosis in cirrhosis: imaging and anticoagulation decisions

An evidence-informed international clinical reference on portal vein thrombosis in cirrhosis, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Variceal bleeding: resuscitation, vasoactive treatment and endoscopy

An evidence-informed international clinical reference on variceal bleeding, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Hepatic encephalopathy: precipitants, lactulose and recurrence prevention

An evidence-informed international clinical reference on hepatic encephalopathy, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Spontaneous bacterial peritonitis: diagnosis, antibiotics and prophylaxis

An evidence-informed international clinical reference on spontaneous bacterial peritonitis, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Ascites in cirrhosis: sodium restriction, diuretics and paracentesis

An evidence-informed international clinical reference on ascites in cirrhosis, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Cirrhosis: diagnosis, staging and prevention of decompensation

An evidence-informed international clinical reference on cirrhosis, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

HepatologyReviewed 2026-08-18
Clinical practice guide

Genetic discrimination, privacy and consent: jurisdiction-sensitive professional practice

An evidence-informed international clinical reference on genetic discrimination, privacy and consent, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Consanguinity and reproductive genetics: risk communication and testing options

An evidence-informed international clinical reference on consanguinity and reproductive genetics, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Newborn genomic testing: indications, consent and family implications

An evidence-informed international clinical reference on newborn genomic testing, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Prenatal diagnostic testing: chorionic villus sampling and amniocentesis principles

An evidence-informed international clinical reference on prenatal diagnostic testing, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Prenatal genetic screening: options, limitations and diagnostic confirmation

An evidence-informed international clinical reference on prenatal genetic screening, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Variants of uncertain significance: interpretation and avoiding overdiagnosis

An evidence-informed international clinical reference on variants of uncertain significance, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Incidental genomic findings: consent, disclosure and follow-up

An evidence-informed international clinical reference on incidental genomic findings, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Pharmacogenomics in prescribing: evidence, limitations and implementation

An evidence-informed international clinical reference on pharmacogenomics in prescribing, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18
Clinical practice guide

Inherited retinal disease: genomic testing and multidisciplinary care

An evidence-informed international clinical reference on inherited retinal disease, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Clinical Genetics & GenomicsReviewed 2026-08-18