MMDPDAMedical & Dental Professional Development Alliance
Evidence for clinical practice

Clinical Knowledge

Structured, referenced clinical resources for healthcare professionals, organised by specialty, profession and resource type, with transparent review and evidence metadata.

600 clinical resources
Clinical practice guide

Sedation and analgesia in intensive care: light sedation and delirium reduction

An evidence-informed international clinical reference on sedation and analgesia in intensive care, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Critical CareReviewed 2026-08-18
Clinical practice guide

Mechanical ventilation: initial settings and bedside reassessment

An evidence-informed international clinical reference on mechanical ventilation, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Critical CareReviewed 2026-08-18
Clinical practice guide

Acute respiratory distress syndrome: lung-protective ventilation and proning

An evidence-informed international clinical reference on acute respiratory distress syndrome, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Critical CareReviewed 2026-08-18
Clinical practice guide

Septic shock: vasopressors, source control and organ support

An evidence-informed international clinical reference on septic shock, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Critical CareReviewed 2026-08-18
Clinical practice guide

Perioperative care of patients with obstructive sleep apnoea

An evidence-informed international clinical reference on perioperative care of patients with obstructive sleep apnoea, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Enhanced recovery after surgery: perioperative principles and implementation

An evidence-informed international clinical reference on enhanced recovery after surgery, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Postoperative delirium: prevention, recognition and management

An evidence-informed international clinical reference on postoperative delirium, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Postoperative respiratory depression: opioid and sedation safety

An evidence-informed international clinical reference on postoperative respiratory depression, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Perioperative anaphylaxis: recognition, adrenaline and investigation

An evidence-informed international clinical reference on perioperative anaphylaxis, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Local anaesthetic systemic toxicity: recognition and lipid rescue

An evidence-informed international clinical reference on local anaesthetic systemic toxicity, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Malignant hyperthermia: recognition and emergency treatment

An evidence-informed international clinical reference on malignant hyperthermia, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Neuraxial anaesthesia and anticoagulation: spinal haematoma prevention

An evidence-informed international clinical reference on neuraxial anaesthesia and anticoagulation, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Postoperative pain: multimodal analgesia and opioid-sparing strategy

An evidence-informed international clinical reference on postoperative pain, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Postoperative nausea and vomiting: risk assessment and multimodal prophylaxis

An evidence-informed international clinical reference on postoperative nausea and vomiting, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Perioperative anaemia and patient blood management

An evidence-informed international clinical reference on perioperative anaemia and patient blood management, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Perioperative diabetes management: fasting, insulin and glucose monitoring

An evidence-informed international clinical reference on perioperative diabetes management, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18
Clinical practice guide

Perioperative management of anticoagulants and antiplatelet medicines

An evidence-informed international clinical reference on perioperative management of anticoagulants and antiplatelet medicines, for healthcare professionals across the UK, US, Canada, Australia, New Zealand and Ireland. It covers recognition, assessment, management, escalation, follow-up and jurisdiction-sensitive practice considerations.

Anaesthesia & Perioperative MedicineReviewed 2026-08-18